RT Journal Article T1 Cost-effectiveness of a primary care-based exercise intervention in perimenopausal women. The FLAMENCO Project. A1 Špacírová, Zuzana A1 Epstein, David A1 García-Mochón, Leticia A1 Aparicio, Virginia A A1 Borges-Cosic, Milkana A1 López Del Amo, M Puerto A1 Martín-Martín, José J K1 Análisis de coste-utilidad K1 Años de vida ajustados por calidad K1 Cost-benefit analysis K1 Ejercicio K1 Exercise K1 Menopause K1 Menopausia K1 Mujeres K1 Quality-adjusted life years K1 Women AB Adequate physical activity levels and a healthy lifestyle may prevent all kinds of non-communicable diseases, promote well-being and reduce health-care costs among perimenopausal women. This study assessed an exercise programme for perimenopausal women. A total of 150 women (aged 45-64 years) not engaged in regular physical activity were randomly assigned to either a 16 week exercise intervention or to the control group. The study was conducted from the perspective of the National Health System. Health outcomes were quality-adjusted life years (QALYs), measured by the EuroQol-5D-5L questionnaire. The total direct costs of the programme were the costs of visits to primary care, specialty care, emergency, medicines, instructor cost and infrastructure cost. The results were expressed as the incremental cost-effectiveness ratio. Sensitivity analysis was undertaken to test the robustness of the analysis. Mean QALYs over 16 weeks were.228 in the control group and.230 in the intervention group (mean difference: .002; 95% confidence interval [95%CI]: -0.005 to 0.009). Improvements from baseline were greater in the intervention group in all dimensions of the EuroQol-5D-5L but not statistically significant. The total costs at the end of the intervention were 160.38 € in the control group and 167.80 € in the intervention group (mean difference: 7.42 €; 95%CI: -47 to 62). The exercise programme had an incremental cost-effectiveness ratio of 4,686 €/QALY. The programme could be considered cost-effective, although the overall difference in health benefits and costs was very modest. Longer term follow-up is needed. YR 2018 FD 2018-10-16 LK http://hdl.handle.net/10668/13108 UL http://hdl.handle.net/10668/13108 LA en DS RISalud RD Apr 11, 2025