TY  - JOUR
AU  - Cismaru, Anca Liliana
AU  - Rudin, Deborah
AU  - Ibañez, Luisa
AU  - Liakoni, Evangelia
AU  - Bonadies, Nicolas
AU  - Kreutz, Reinhold
AU  - Carvajal, Alfonso
AU  - Lucena, Maria Isabel
AU  - Martin, Javier
AU  - Sancho Ponce, Esther
AU  - Molokhia, Mariam
AU  - Eriksson, Niclas
AU  - EuDAC Collaborators,
AU  - Krähenbühl, Stephan
AU  - Largiadèr, Carlo R
AU  - Haschke, Manuel
AU  - Hallberg, Pär
AU  - Wadelius, Mia
AU  - Amstutz, Ursula
PY  - 2020
DO  - 10.3390/genes11111275
UR  - http://hdl.handle.net/10668/16529
T2  - Genes
AB  - Agranulocytosis is a rare yet severe idiosyncratic adverse drug reaction to metamizole, an analgesic widely used in countries such as Switzerland and Germany. Notably, an underlying mechanism has not yet been fully elucidated and no predictive factors...
LA  - en
KW  - dipyrone
KW  - drug-induced agranulocytosis
KW  - genome-wide association study
KW  - metamizole
KW  - pharmacogenetics
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Agranulocytosis
KW  - Biomarkers, Pharmacological
KW  - Case-Control Studies
KW  - Dipyrone
KW  - Europe
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Genome-Wide Association Study
KW  - Germany
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Neutropenia
KW  - Retrospective Studies
KW  - Switzerland
TI  - Genome-Wide Association Study of Metamizole-Induced Agranulocytosis in European Populations.
TY  - research article
VL  - 11
ER  -