TY  - JOUR
AU  - Jiménez, G.
AU  - López-Ruiz, E.
AU  - Kwiatkowski, W.
AU  - Montañez, E.
AU  - Arrebola, F.
AU  - Carrillo, E.
AU  - Gray, P. C.
AU  - Izpisua Belmonte, J. C.
AU  - Choe, S.
AU  - Perán, M.
AU  - Marchal, J. A.
PY  - 2015
DO  - 10.1038/srep16400
UR  - http://hdl.handle.net/10668/2314
T2  - Scientific Reports
AB  - Autologous chondrocyte implantation (ACI) depends on the quality and quantity of implanted cells and is hindered by the fact that chondrocytes cultured for long periods of time undergo dedifferentiation. Here we have developed a reproducible and...
LA  - en
PB  - Nature Publishing Group
KW  - Activinas
KW  - Animales
KW  - Biopsia
KW  - Cartílago articular
KW  - Condrocitos
KW  - Colágeno
KW  - Matriz extracelular
KW  - Humanos
KW  - Osteoartritis
KW  - Proteoglicanos
KW  - Reacción en cadena de la polimerasa de transcriptasa inversa
KW  - Tejido subcutáneo
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Gonadal Hormones::Activins
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Cytodiagnosis::Biopsy
KW  - Medical Subject Headings::Anatomy::Musculoskeletal System::Cartilage::Hyaline Cartilage::Cartilage, Articular
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Chondrocytes
KW  - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers::Biopolymers::Collagen
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Extracellular Space::Extracellular Matrix
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Diseases::Musculoskeletal Diseases::Rheumatic Diseases::Osteoarthritis
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Polysaccharides::Proteoglycans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Nucleic Acid Amplification Techniques::Polymerase Chain Reaction::Reverse Transcriptase Polymerase Chain Reaction
KW  - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Subcutaneous Tissue
TI  - Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes.
TY  - research article
ER  -