RT Journal Article T1 Urinary Microbiome: Yin and Yang of the Urinary Tract A1 Perez-Carrasco, Virginia A1 Soriano-Lerma, Ana A1 Soriano, Miguel A1 Gutiérrez-Fernández, José A1 Garcia-Salcedo, Jose A. K1 Microbiome K1 Urinary tract K1 Infection K1 Disease K1 Health K1 Sequencing K1 Microbiota K1 Sistema urinario K1 Infecciones K1 Enfermedad K1 Salud K1 Datos de secuencia molecular AB The application of next generation sequencing techniques has allowed the characterization of the urinary tract microbiome and has led to the rejection of the pre-established concept of sterility in the urinary bladder. Not only have microbial communities in the urinary tract been implicated in the maintenance of health but alterations in their composition have also been associated with different urinary pathologies, such as urinary tract infections (UTI). Therefore, the study of the urinary microbiome in healthy individuals, as well as its involvement in disease through the proliferation of opportunistic pathogens, could open a potential field of study, leading to new insights into prevention, diagnosis and treatment strategies for urinary pathologies. In this review we present an overview of the current state of knowledge about the urinary microbiome in health and disease, as well as its involvement in the development of new therapeutic strategies. PB Frontiers YR 2021 FD 2021-05-18 LK http://hdl.handle.net/10668/4064 UL http://hdl.handle.net/10668/4064 LA en NO Perez-Carrasco V, Soriano-Lerma A, Soriano M, Gutiérrez-Fernández J, Garcia-Salcedo JA. Urinary Microbiome: Yin and Yang of the Urinary Tract. Front Cell Infect Microbiol. 2021 May 18;11:617002 DS RISalud RD Jun 1, 2025