TY - JOUR AU - Serrano, César AU - Vivancos, Ana AU - López-Pousa, Antonio AU - Matito, Judit AU - Mancuso, Francesco M AU - Valverde, Claudia AU - Quiroga, Sergi AU - Landolfi, Stefania AU - Castro, Sandra AU - Dopazo, Cristina AU - Sebio, Ana AU - Virgili, Anna C AU - Menso, María M AU - Martín-Broto, Javier AU - Sansó, Miriam AU - García-Valverde, Alfonso AU - Rosell, Jordi AU - Fletcher, Jonathan A AU - George, Suzanne AU - Carles, Joan AU - Arribas, Joaquín PY - 2020 DO - 10.1186/s12885-020-6597-x UR - http://hdl.handle.net/10668/15051 T2 - BMC cancer AB - Gastrointestinal stromal tumor (GIST) initiation and evolution is commonly framed by KIT/PDGFRA oncogenic activation, and in later stages by the polyclonal expansion of resistant subpopulations harboring KIT secondary mutations after the onset of... LA - en KW - Circulating tumor DNA KW - Gastrointestinal stromal tumor KW - Imatinib KW - KIT KW - Liquid biopsy KW - PDGFRA KW - Regorafenib KW - Sarcoma KW - Sunitinib KW - Adult KW - Aged KW - Biomarkers, Tumor KW - Cell-Free Nucleic Acids KW - Circulating Tumor DNA KW - Exons KW - Female KW - Gastrointestinal Stromal Tumors KW - Genotype KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Liquid Biopsy KW - Male KW - Middle Aged KW - Molecular Targeted Therapy KW - Mutation KW - Neoplasm Metastasis KW - Polymerase Chain Reaction KW - Prognosis KW - Protein Kinase Inhibitors KW - Tumor Burden TI - Clinical value of next generation sequencing of plasma cell-free DNA in gastrointestinal stromal tumors. TY - research article VL - 20 ER -