RT Journal Article
T1 Total and subtypes of dietary fat intake and risk of type 2 diabetes mellitus in the Prevención con Dieta Mediterránea (PREDIMED) study.
A1 Guasch-Ferré, Marta
A1 Becerra-Tomás, Nerea
A1 Ruiz-Canela, Miguel
A1 Corella, Dolores
A1 Schröder, Helmut
A1 Estruch, Ramon
A1 Ros, Emilio
A1 Arós, Fernando
A1 Gómez-Gracia, Enrique
A1 Fiol, Miquel
A1 Serra-Majem, Lluís
A1 Lapetra, José
A1 Basora, Josep
A1 Martín-Calvo, Nerea
A1 Portoles, Olga
A1 Fitó, Montserrat
A1 Hu, Frank B
A1 Forga, Lluís
A1 Salas-Salvadó, Jordi
K1 PREDIMED study
K1 dietary fat
K1 fat subtypes
K1 monounsaturated fat
K1 saturated fat
K1 type 2 diabetes
K1 ω-3 fatty acids
AB Background: The associations between dietary fat and cardiovascular disease have been evaluated in several studies, but less is known about their influence on the risk of diabetes.Objective: We examined the associations between total fat, subtypes of dietary fat, and food sources rich in saturated fatty acids and the incidence of type 2 diabetes (T2D).Design: A prospective cohort analysis of 3349 individuals who were free of diabetes at baseline but were at high cardiovascular risk from the PREvención con DIeta MEDiterránea (PREDIMED) study was conducted. Detailed dietary information was assessed at baseline and yearly during the follow-up using a food frequency questionnaire. Multivariable Cox proportional hazards models were used to estimate T2D HRs and 95% CIs according to baseline and yearly updated fat intake.Results: We documented 266 incident cases during 4.3 y of follow-up. Baseline saturated and animal fat intake was not associated with the risk of T2D. After multivariable adjustment, participants in the highest quartile of updated intake of saturated and animal fat had a higher risk of diabetes than the lowest quartile (HR: 2.19; 95% CI: 1.28, 3.73; and P-trend = 0.01 compared with HR: 2.00; 95% CI: 1.29, 3.09; and P-trend
YR 2017
FD 2017-02-15
LK http://hdl.handle.net/10668/10866
UL http://hdl.handle.net/10668/10866
LA en
DS RISalud
RD Apr 12, 2025