RT Journal Article T1 Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review A1 Ubago-Guisado, Esther A1 Rodríguez-Barranco, Miguel A1 Ching-López, Ana A1 Petrova, Dafina A1 Molina-Montes, Esther A1 Amiano, Pilar A1 Barricarte-Gurrea, Aurelio A1 Chirlaque, María-Dolores A1 Agudo, Antonio A1 Sanchez-Perez, Maria-Jose K1 Colorectal cancer K1 Breast cancer K1 Lung cancer K1 Prostate cancer K1 Intake K1 Alcohol K1 Fruits K1 Vegetables K1 Meat K1 Fish K1 Neoplasias colorrectales K1 Neoplasias de la mama K1 Neoplasias pulmonares K1 Neoplasias de la próstata K1 Ingestión de alimentos K1 Etanol K1 Frutas K1 Verduras K1 Carne K1 Revisión sistemática K1 Metaanalisis AB The European Prospective Investigation into Cancer and Nutrition (EPIC) is a multicentre prospective study conducted in 23 centres in 10 European countries. Here we review the findings from EPIC on the relationship between diet-related exposures and incidence or mortality from the four most frequent cancers in the European population: colorectal, breast, lung, and prostate cancer. We conducted a systematic review following PRISMA guidelines and identified 110 high-quality studies based on the EPIC cohort. Fruit and vegetable consumption had a protective effect against colorectal, breast, and lung cancer, whereas only fruit had a protective effect against prostate cancer. A higher consumption of fish and lower consumption of red and processed meat were related with a lower risk of colorectal cancer; and higher consumption of fatty fish with lower risk of breast cancer. Calcium and yogurt intake were found to protect against colorectal and prostate cancer. Alcohol consumption increased the risk for colorectal and breast cancer. Finally, adherence to the Mediterranean diet emerged as a protective factor for colorectal and breast cancer. The EPIC study results are in agreement with the latest evidence from leading authorities on cancer prevention and help to inform public prevention policies and strategies. PB MDPI YR 2021 FD 2021-10-13 LK http://hdl.handle.net/10668/4464 UL http://hdl.handle.net/10668/4464 LA en NO Ubago-Guisado E, Rodríguez-Barranco M, Ching-López A, Petrova D, Molina-Montes E, Amiano P, et al. Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review. Nutrients. 2021 Oct 13;13(10):3582 DS RISalud RD Apr 3, 2025