TY  - JOUR
AU  - Quintanal-Villalonga, Álvaro
AU  - Ferrer, Irene
AU  - Guruceaga, Elizabeth
AU  - Cirauqui, Cristina
AU  - Marrugal, Ángela
AU  - Ojeda, Laura
AU  - García, Santiago
AU  - Zugazagoitia, Jon
AU  - Muñoz-Galván, Sandra
AU  - Lopez-Rios, Fernando
AU  - Montuenga, Luis
AU  - Vicent, Silvestre
AU  - Molina-Pinelo, Sonia
AU  - Carnero, Amancio
AU  - Paz-Ares, Luis
PY  - 2020
DO  - 10.1016/j.ebiom.2020.102683
UR  - http://hdl.handle.net/10668/4460
T2  - EBioMedicine
AB  - Background: Fibroblast growth factor receptor (FGFR)1 and FGFR4 have been associated with tumorigenesis in a variety of tumour types. As a therapeutic approach, their inhibition has been attempted in different types of malignancies, including lung...
LA  - en
PB  - Elsevier
KW  - FGFR1
KW  - FGFR4
KW  - N-cadherin
KW  - Predictive biomarker
KW  - FGFR inhibitors
KW  - Fibroblast growth factor receptor 1
KW  - Fibroblast growth factor receptor 4
KW  - Biomarkers
KW  - Lung neoplasms
KW  - Cadherinas
KW  - Receptor tipo 1 de factor de crecimiento de fibroblastos
KW  - Receptor tipo 4 de factor de crecimiento de fibroblastos
KW  - Biomarcadores
KW  - Neoplasias pulmonares
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Benzamides
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Glycoproteins::Membrane Glycoproteins::Cell Adhesion Molecules::Cadherins
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms::Bronchial Neoplasms::Carcinoma, Bronchogenic::Carcinoma, Non-Small-Cell Lung
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, Nude
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperazines
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Pyrazoles
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptor,...
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptor,...
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Tumor Cells, Cultured
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Neoplasm
TI  - FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy
TY  - research article
ER  -