RT Journal Article
T1 Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women.
A1 Del Pozo, Maria Del Pilar
A1 Lope, Virginia
A1 Criado-Navarro, Inmaculada
A1 Pastor-Barriuso, Roberto
A1 Fernandez de Larrea, Nerea
A1 Ruiz, Emma
A1 Castello, Adela
A1 Lucas, Pilar
A1 Sierra, Angeles
A1 Romieu, Isabelle
A1 Chajes, Veronique
A1 Priego-Capote, Feliciano
A1 Perez-Gomez, Beatriz
A1 Pollan, Marina
K1 body mass index
K1 desaturation index
K1 fat
K1 fatty acids
K1 obesity
AB This study investigates the still uncertain association between serum phospholipid fatty acids (PL-FA), and anthropometric and adiposity variables. A cross-sectional study was conducted with 1443 Spanish premenopausal women. Participants answered an epidemiological and a food frequency questionnaire. Anthropometric variables were measured using a bioimpedance scale. Serum PL-FAs levels were determined by gas chromatography-mass spectrometry. The association between body mass index (BMI), weight gain, body fat percentage, visceral fat index, and waist circumference with serum PL-FAs and desaturation indices was evaluated using multivariable linear regression models. BMI was positively associated with the relative concentration of saturated fatty acids (SFAs) (β = 0.94, q-val = 0.001), and with palmitoleic, dihomo-γ-linolenic (DGLA), arachidonic (AA) and α-linolenic acids, and was inversely associated with oleic, gondoic, trans-vaccenic, linoleic and γ-linolenic acids. Total fat percentage was positively associated with DGLA and AA, and inversely with linoleic and γ-linolenic acids. Low relative concentrations of some SFAs and high levels of n-6 PUFAs were associated with greater waist circumference. While the oleic/stearic and AA/DGLA acid ratios were inversely associated with BMI, DGLA/linoleic acid ratio was positively related to almost all variables. In addition to BMI, total fat percentage and waist circumference were also associated with certain individual fatty acids.
PB MDPI AG
YR 2020
FD 2020-06-23
LK http://hdl.handle.net/10668/15883
UL http://hdl.handle.net/10668/15883
LA en
NO Del Pozo MDP, Lope V, Criado-Navarro I, Pastor-Barriuso R, Fernández de Larrea N, et al. Serum Phospholipid Fatty Acids Levels, Anthropometric Variables and Adiposity in Spanish Premenopausal Women. Nutrients. 2020 Jun 25;12(6):1895.
DS RISalud
RD Jul 31, 2025