TY  - JOUR
AU  - Kim, Hanna
AU  - Calatayud, Carles
AU  - Guha, Sanjib
AU  - Fernandez-Carasa, Irene
AU  - Berkowitz, Laura
AU  - Carballo-Carbajal, Iria
AU  - Ezquerra, Mario
AU  - Fernandez-Santiago, Ruben
AU  - Kapahi, Pankaj
AU  - Raya, Angel
AU  - Miranda-Vizuete, Antonio
AU  - Lizcano, Jose Miguel
AU  - Vila, Miquel
AU  - Caldwell, Kim A
AU  - Caldwell, Guy A
AU  - Consiglio, Antonella
AU  - Dalfo, Esther
PY  - 2018
DO  - 10.1007/s12035-018-0881-7
UR  - http://hdl.handle.net/10668/12113
T2  - Molecular neurobiology
AB  - Parkinson's disease is associated with intracellular α-synuclein accumulation and ventral midbrain dopaminergic neuronal death in the Substantia Nigra of brain patients. The Rho GTPase pathway, mainly linking surface receptors to the organization of...
LA  - en
PB  - Springer
KW  - Alpha-synuclein accumulation
KW  - Autophagy impairment
KW  - Dopaminergic neurons
KW  - Parkinson’s disease
KW  - RAC1/ced-10
KW  - Amyloid
KW  - Animals
KW  - Autophagy
KW  - Behavior, Animal
KW  - Biomarkers
KW  - Caenorhabditis elegans
KW  - Caenorhabditis elegans Proteins
KW  - Cell Death
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Dopamine
KW  - Dopaminergic Neurons
KW  - Humans
KW  - Inclusion Bodies
KW  - Induced Pluripotent Stem Cells
KW  - Mesencephalon
KW  - Mutation
KW  - Neurites
KW  - Neuroprotection
KW  - Parkinson Disease
KW  - alpha-Synuclein
KW  - rac GTP-Binding Proteins
KW  - rac1 GTP-Binding Protein
TI  - The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.
TY  - research article
VL  - 55
ER  -