TY  - JOUR
AU  - Villar, Victor Hugo
AU  - Vögler, Oliver
AU  - Barceló, Francisca
AU  - Martín-Broto, Javier
AU  - Martínez-Serra, Jordi
AU  - Ruiz-Gutiérrez, Valentina
AU  - Alemany, Regina
PY  - 2016
DO  - 10.1371/journal.pone.0155946
UR  - http://hdl.handle.net/10668/10118
T2  - PloS one
AB  - Several important biological activities have been attributed to the pentacyclic triterpene ursolic acid (UA), being its antitumoral effect extensively studied in human adenocarcinomas. In this work, we focused on the efficacy and molecular mechanisms...
LA  - en
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Apoptosis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cell Survival
KW  - Down-Regulation
KW  - Doxorubicin
KW  - Drug Synergism
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Proto-Oncogene Proteins c-akt
KW  - Sarcoma
KW  - Signal Transduction
KW  - Triterpenes
TI  - Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma.
TY  - research article
VL  - 11
ER  -