RT Journal Article
T1 Immunological Landscape and Clinical Management of Rectal Cancer.
A1 Pérez-Ruiz, Elísabeth
A1 Berraondo, Pedro
K1 chemotherapy
K1 immune system
K1 predictive factors
K1 radiotherapy
K1 rectal cancer
AB The clinical management of rectal cancer and colon cancer differs due to increased local relapses in rectal cancer. However, the current molecular classification does not differentiate rectal cancer and colon cancer as two different entities. In recent years, the impact of the specific immune microenvironment in cancer has attracted renewed interest and is currently recognized as one of the major determinants of clinical progression in a wide range of tumors. In colorectal cancer, the density of lymphocytic infiltration is associated with better overall survival. Due to the need for biomarkers of response to conventional treatment with chemoradiotherapy in rectal tumors, the immune status of rectal cancer emerges as a useful tool to improve the management of patients.
SN 1664-3224
YR 2016
FD 2016-02-22
LK https://hdl.handle.net/10668/26748
UL https://hdl.handle.net/10668/26748
LA en
DS RISalud
RD Apr 12, 2025