TY  - JOUR
AU  - Pérez, Irene
AU  - Campos-Pardos, Elena
AU  - Díaz, Caridad
AU  - Uranga, Santiago
AU  - Sayes, Fadel
AU  - Vicente, Francisca
AU  - Aguiló, Nacho
AU  - Brosch, Roland
AU  - Martín, Carlos
AU  - Gonzalo-Asensio, Jesús
PY  - 2022
DO  - 10.1016/j.omtn.2022.02.011
SN  - 2162-2531
UR  - http://hdl.handle.net/10668/22460
T2  - Molecular therapy. Nucleic acids
AB  - Cyclic (di)nucleotides act as universal second messengers endogenously produced by several pathogens. Specifically, the roles of c-di-AMP in Mycobacterium tuberculosis immunity and virulence have been largely explored, although its contribution to the...
LA  - en
KW  - BCG
KW  - IFN
KW  - MT:therapies and applications
KW  - MTBVAC
KW  - PhoPR
KW  - cyclic dinucleotides
KW  - innate immunity
KW  - live vaccines
KW  - tuberculosis
TI  - The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy.
TY  - research article
VL  - 27
ER  -