TY  - JOUR
AU  - Lacámara, Nerea
AU  - Lecumberri, Beatriz
AU  - Barquiel, Beatriz
AU  - Escribano, Arancha
AU  - González-Casado, Isabel
AU  - Álvarez-Escolá, Cristina
AU  - Aleixandre-Blanquer, Fernando
AU  - Morales, Francisco
AU  - Alfayate, Rocío
AU  - Bernal-Soriano, Mari Carmen
AU  - Miralles, Raquel
AU  - Yildirim Simsir, Ilgin
AU  - Özgen, Ahmet Gökhan
AU  - Bernal, Juan
AU  - Berbel, Pere
AU  - Moreno, Jose Carlos
PY  - 2020
DO  - 10.1089/thy.2019.0825
UR  - http://hdl.handle.net/10668/15683
T2  - Thyroid : official journal of the American Thyroid Association
AB  - Background: Thyroxine (T4) to triiodothyronine (T3) deiodination in the hypothalamus/pituitary is mediated by deiodinase type-2 (D2) activity. Dio2(-/-) mice show central resistance to exogenous T4. Patients with resistance to exogenous thyroxine...
LA  - en
KW  - RETH
KW  - T4+T3 therapy for hypothyroidism
KW  - biomarker T3/rT3 ratio
KW  - iatrogenic hyperthyroidism
KW  - iodothyronine ratios
KW  - resistance to levothyroxine
KW  - thyroid hormone metabolism
KW  - Adult
KW  - Biomarkers
KW  - Child, Preschool
KW  - Drug Resistance
KW  - Female
KW  - Humans
KW  - Hyperthyroidism
KW  - Hypothyroidism
KW  - Iatrogenic Disease
KW  - Male
KW  - Middle Aged
KW  - Thyrotoxicosis
KW  - Thyrotropin
KW  - Thyroxine
KW  - Time Factors
KW  - Treatment Outcome
KW  - Young Adult
TI  - Identification of Resistance to Exogenous Thyroxine in Humans.
TY  - research article
VL  - 30
ER  -