TY  - JOUR
AU  - Sánchez-Maldonado, Jose Manuel
AU  - Cáliz, Rafael
AU  - López-Nevot, Miguel Ángel
AU  - Cabrera-Serrano, Antonio José
AU  - Moñiz-Díez, Ana
AU  - Canhão, Helena
AU  - Ter Horst, Rob
AU  - Quartuccio, Luca
AU  - Sorensen, Signe B
AU  - Glintborg, Bente
AU  - Hetland, Merete L
AU  - Filipescu, Ileana
AU  - Pérez-Pampin, Eva
AU  - Conesa-Zamora, Pablo
AU  - Swierkot, Jerzy
AU  - den Broeder, Alfons A
AU  - De Vita, Salvatore
AU  - Petersen, Eva Rabing Brix
AU  - Li, Yang
AU  - Ferrer, Miguel A
AU  - Escudero, Alejandro
AU  - Netea, Mihai G
AU  - Coenen, Marieke J H
AU  - Andersen, Vibeke
AU  - Fonseca, João E
AU  - Jurado, Manuel
AU  - Bogunia-Kubik, Katarzyna
AU  - Collantes, Eduardo
AU  - Sainz, Juan
PY  - 2021
DO  - 10.3389/fimmu.2021.672255
UR  - https://hdl.handle.net/10668/25695
T2  - Frontiers in immunology
AB  - We aimed to validate the association of 28 GWAS-identified genetic variants for response to TNF inhibitors (TNFi) in a discovery cohort of 1361 rheumatoid arthritis (RA) patients monitored in routine care and ascertained through the REPAIR consortium...
LA  - en
KW  - GWAS
KW  - TNF inhibitors
KW  - drug response
KW  - genetic variant
KW  - rheumatoid arthritis
KW  - Adult
KW  - Aged
KW  - Alleles
KW  - Arthritis, Rheumatoid
KW  - Biomarkers
KW  - Cohort Studies
KW  - Disease Susceptibility
KW  - Female
KW  - Genetic Variation
KW  - Genome-Wide Association Study
KW  - Genotype
KW  - Humans
KW  - Linkage Disequilibrium
KW  - Male
KW  - Middle Aged
KW  - Pharmacogenomic Variants
KW  - Polymorphism, Single Nucleotide
KW  - Registries
KW  - Treatment Outcome
KW  - Tumor Necrosis Factor Inhibitors
TI  - Validation of GWAS-Identified Variants for Anti-TNF Drug Response in Rheumatoid Arthritis: A Meta-Analysis of Two Large Cohorts.
TY  - research article
VL  - 12
ER  -