TY - JOUR AU - Medrano, Luz María AU - Taxonera, Carlos AU - González-Artacho, Cristina AU - Pascual, Virginia AU - Gómez-García, María AU - Barreiro-de Acosta, Manuel AU - Pérez-Calle, José L AU - Bermejo, Fernando AU - López-Sanromán, Antonio AU - Martín Arranz, Dolores AU - Gisbert, Javier P AU - Mendoza, Juan Luis AU - Martín, Javier AU - Núñez, Concepción AU - Urcelay, Elena PY - 2015 DO - 10.1155/2015/318207 SN - 0962-9351 UR - http://hdl.handle.net/10668/2041 T2 - Mediators of inflammation AB - Substantial proportion of Crohn's disease (CD) patients shows no response or a limited response to treatment with infliximab (IFX) and to identify biomarkers of response would be of great clinical and economic benefit. The expression profile of five... LA - en PB - Hindawi Publishing Corporation KW - Anticuerpos monoclonales KW - Marcadores biológicos KW - Enfermedad de Crohn KW - Genotipo KW - Haplotipos KW - Humanos KW - Íleon KW - Colon KW - Interleucina-11 KW - Polimorfismo genético KW - Factor de necrosis tumoral alfa KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Antibodies, Monoclonal KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers KW - Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Inflammatory Bowel Diseases::Crohn Disease KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Haplotypes KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, Small::Ileum KW - Medical Subject Headings::Anatomy::Digestive System::Gastrointestinal Tract::Intestines::Intestine, Large::Colon KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukins::Interleukin-11 KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Intercellular Signaling Peptides and Proteins::Tumor Necrosis Factors::Tumor Necrosis Factor-alpha TI - Response to Infliximab in Crohn's Disease: Genetic Analysis Supporting Expression Profile. TY - research article ER -