RT Journal Article T1 Determinants of Longitudinal Changes in Cardiometabolic Risk in Adolescents with Overweight/Obesity: The EVASYON Study. A1 Martin-Matillas, Miguel A1 Rocha-Silva, Dinalrilan A1 Plaza-Florido, Abel A1 Delgado-Fernández, Manuel A1 Marti, Amelia A1 De Miguel-Etayo, Pilar A1 Moreno, Luis A A1 Marcos, Ascensión A1 Campoy, Cristina K1 adiposity K1 adolescents K1 birthweight K1 blood pressure K1 breastfeeding K1 cardiorespiratory fitness K1 cholesterol K1 lifestyle intervention K1 parents’ educational level K1 parents’ occupational level AB We investigated which determinants (socioeconomic, early life factors, body composition changes, fitness changes and/or physical activity changes) best predicted longitudinal outcomes in cardiometabolic risk profile (Z-score change) in adolescents with OW/OB who underwent a 13-month multidisciplinary lifestyle intervention. A total of 165 adolescents (13-16 y; 46% boys) from the EVASYON study were included. Socioeconomic variables and early life factors were obtained from the medical records. Body composition was assessed using anthropometry. Fitness and physical activity were measured with field-based tests and questionnaires. Cardiometabolic risk factors (fasting glucose, HDL cholesterol, triglycerides, blood pressure and waist circumference) were derived from standard methods in the hospital. Body weight changes, sex and mother's education were selected in the stepwise process as the most important determinants of changes in cardiometabolic risk profile (R2 = 0.26, p = 0.002; R2 = 0.14, p = 0.013; and R2 = 0.14, p = 0.017, respectively). Both boys and girls showed a lower cardiometabolic risk score with the reduction in body weight (r = 0.535, p = 0.009 and r = 0.506, p = 0.005, respectively). There was no interaction between sex and body weight change (p = 0.614). In conclusion, the simple measure of changes in body weight should be considered to track changes in cardiometabolic risk profile in adolescents with OW/OB. PB MDPI AG YR 2022 FD 2022-08-05 LK http://hdl.handle.net/10668/21493 UL http://hdl.handle.net/10668/21493 LA en NO Martín-Matillas M, Rocha-Silva D, Plaza-Florido A, Delgado-Fernández M, Marti A, De Miguel-Etayo P, et al. Determinants of Longitudinal Changes in Cardiometabolic Risk in Adolescents with Overweight/Obesity: The EVASYON Study. Nutrients. 2022 Aug 8;14(15):3241. DS RISalud RD Apr 18, 2025