TY - JOUR AU - Soria-Bretones, Isabel AU - Cepeda-GarcĂ­a, Cristina AU - Checa-Rodriguez, Cintia AU - Heyer, Vincent AU - Reina-San-Martin, Bernardo AU - Soutoglou, Evi AU - Huertas, Pablo PY - 2017 DO - 10.1038/s41467-017-00183-6 UR - http://hdl.handle.net/10668/11435 T2 - Nature communications AB - DNA breaks are complex DNA lesions that can be repaired by two alternative mechanisms: non-homologous end-joining and homologous recombination. The decision between them depends on the activation of the DNA resection machinery, which blocks... LA - en KW - Blotting, Western KW - Carrier Proteins KW - Cell Line, Tumor KW - DNA KW - DNA Breaks, Double-Stranded KW - DNA End-Joining Repair KW - Endodeoxyribonucleases KW - HEK293 Cells KW - Homologous Recombination KW - Humans KW - Ligases KW - Microscopy, Confocal KW - Nuclear Proteins KW - Polycomb-Group Proteins KW - RNA Interference KW - SUMO-1 Protein KW - Small Ubiquitin-Related Modifier Proteins KW - Sumoylation TI - DNA end resection requires constitutive sumoylation of CtIP by CBX4. TY - research article VL - 8 ER -