RT Journal Article
T1 Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder.
A1 Hmadcha, Abdelkrim
A1 Aguilera, Yolanda
A1 Lozano-Arana, Maria Dolores
A1 Mellado, Nuria
A1 Sánchez, Javier
A1 Moya, Cristina
A1 Sánchez-Palazón, Luis
A1 Palacios, Jose
A1 Antiñolo, Guillermo
A1 Soria, Bernat
K1 Células madre embrionarias
K1 Fertilización in Vitro
K1 Investigación básica
K1 Investigaciones con embriones
AB From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) HVR1, HVR2 and HVR3 were successfully derived. HVR1 was assumed to be genetically normal, HVR2 carrying Becker muscular dystrophy and HVR3 Hemophilia B. Despite the translocation t(9;15)(q34.3;q14) detected in HVR2, all the 3 cell lines were characterised in vitro and in vivo as normal hESCs lines and were registered in the Spanish Stem Cell Bank.
PB Elsevier
SN 1873-5061
YR 2016
FD 2016-05
LK http://hdl.handle.net/10668/2247
UL http://hdl.handle.net/10668/2247
LA spa
NO Hmadcha A, Aguilera Y, Lozano-Arana MD, Mellado N, Sánchez J, Moya C, et al. Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder. Stem Cell Res. 2016;16(3):635-9
NO Lab resource
DS RISalud
RD Apr 19, 2025