TY - JOUR AU - De Luca, Andrea AU - Flandre, Philippe AU - Dunn, David AU - Zazzi, Maurizio AU - Wensing, Annemarie AU - Santoro, Maria Mercedes AU - Günthard, Huldrych F AU - Wittkop, Linda AU - Kordossis, Theodoros AU - Garcia, Federico AU - Castagna, Antonella AU - Cozzi-Lepri, Alessandro AU - Churchill, Duncan AU - De Wit, Stéphane AU - Brockmeyer, Norbert H AU - Imaz, Arkaitz AU - Mussini, Cristina AU - Obel, Niels AU - Perno, Carlo Federico AU - Roca, Bernardino AU - Reiss, Peter AU - Schülter, Eugen AU - Torti, Carlo AU - van Sighem, Ard AU - Zangerle, Robert AU - Descamps, Diane AU - CHAIN and COHERE in EuroCoord PY - 2016 DO - 10.1093/jac/dkv465 UR - http://hdl.handle.net/10668/9793 T2 - The Journal of antimicrobial chemotherapy AB - The objective of this study was to improve the prediction of the impact of HIV-1 protease mutations in different viral subtypes on virological response to darunavir. Darunavir-containing treatment change episodes (TCEs) in patients previously failing... LA - en KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Anti-HIV Agents KW - Darunavir KW - Drug Resistance, Viral KW - Europe KW - Female KW - Genotyping Techniques KW - HIV Infections KW - HIV Protease KW - HIV-1 KW - Humans KW - Male KW - Microbial Sensitivity Tests KW - Middle Aged KW - Mutation KW - Prognosis KW - Treatment Outcome KW - Young Adult TI - Improved darunavir genotypic mutation score predicting treatment response for patients infected with HIV-1 subtype B and non-subtype B receiving a salvage regimen. TY - research article VL - 71 ER -