RT Journal Article T1 Fatty acid status and antioxidant defense system in mothers and their newborns after salmon intake during late pregnancy. A1 Garcia-Rodriguez, Cruz E A1 Olza, Josune A1 Mesa, Maria D A1 Aguilera, Concepcion M A1 Miles, Elizabeth A A1 Noakes, Paul S A1 Vlachava, Maria A1 Kremmyda, Lefkothea-Stella A1 Diaper, Norma D A1 Godfrey, Keith M A1 Calder, Philip C A1 Gil, Angel K1 Antioxidants K1 Fatty acids K1 Fish oils K1 Newborn K1 Pregnancy K1 ω-3 AB The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defense system after the intake of two portions of salmon per week during late pregnancy. Pregnant women (N = 123) were randomly assigned to continue their habitual diet, which was low in oily fish (control group, n = 61) or to consume two 150-g salmon portions per week (salmon group, n = 62) beginning at 20 wk of gestation and lasting until delivery. Fatty acids, selenium, and glutathione concentrations and antioxidant defense enzyme activities were measured in maternal erythrocytes at 20, 34, and 38 wk of pregnancy, and in cord erythrocytes collected at birth. Plasma concentrations of antioxidant molecules were measured. Compared with the control group, consuming salmon had little effect on erythrocyte fatty acids in either mothers or newborns. Components of the antioxidant defense system did not differ between groups. Glutathione peroxidase activity and the concentrations of tocopherols, retinol, and coenzyme Q10 were significantly lower in cord blood compared with maternal blood at week 38 in both groups. Maternal and newborn erythrocyte fatty acids are not strongly affected by the intake of two portions of salmon per week during the second half of pregnancy, although erythrocyte docosahexaenoic acid might be increased in newborns. Maternal and newborn antioxidant defense systems are not impaired by intake of salmon from 20 wk gestation. PB Elsevier Inc. YR 2016 FD 2016-06-08 LK http://hdl.handle.net/10668/10344 UL http://hdl.handle.net/10668/10344 LA en NO Garcia-Rodriguez CE, Olza J, Mesa MD, Aguilera CM, Miles EA, Noakes PS, et al. Fatty acid status and antioxidant defense system in mothers and their newborns after salmon intake during late pregnancy. Nutrition. 2017 Jan;33:157-162. DS RISalud RD Apr 6, 2025