RT Journal Article
T1 Epidemiology of paratuberculosis in sheep and goats in southern Spain.
A1 Jimenez-Martin, Debora
A1 Garcia-Bocanegra, Ignacio
A1 Risalde, Maria A
A1 Fernandez-Molera, Vicente
A1 Jimenez-Ruiz, Saul
A1 Isla, Julio
A1 Cano-Terriza, David
K1 Animal health
K1 Mycobacterium avium
K1 Paratuberculosis
K1 Risk-based
K1 Seroprevalence
K1 Small ruminants
K1 Surveillance
AB Paratuberculosis is a worldwide, chronic infectious disease caused by Mycobacterium avium subsp. paratuberculosis (MAP) that mainly affects ruminant species. This disease has a significant economic impact on small ruminant production due to the costs of implementing control measures and production losses. A cross-sectional study was carried out to determine the seroprevalence, spatial distribution and risk factors associated with MAP exposure in sheep and goats in Andalusia (southern Spain). Serum samples from 4134 small ruminants (2266 sheep and 1868 goats) in 153 flocks were tested by an in-house ELISA for antibodies against MAP using paratuberculosis protoplasmic antigen 3 (PPA3) as coating antigen. Antibodies against MAP were detected in 8.1% (183/2266; 95% CI: 7.0-9.2%) of sheep and 20.0% (374/1868; 95% CI: 18.2-21.8%) of goats. The true individual seroprevalence was 8.4% (95% CI: 6.9-10.1%) in sheep and 25.2% (95% CI: 22.7-27.8%) in goats. Seropositivity was detected in 66.3% (55/83; 95% CI: 56.1-76.4%) of sheep herds and 90.0% (63/70; 95% CI: 83.0-97.0%) of goat herds. Spatial analysis identified three statistically significant clusters (p 
PB Elsevier
YR 2022
FD 2022-03-28
LK http://hdl.handle.net/10668/22478
UL http://hdl.handle.net/10668/22478
LA en
NO Jiménez-Martín D, García-Bocanegra I, Risalde MA, Fernández-Molera V, Jiménez-Ruiz S, Isla J, et al. Epidemiology of paratuberculosis in sheep and goats in southern Spain. Prev Vet Med. 2022 May;202:105637
NO This study was partially funded by the Spanish Ministry of Economy and Competitiveness (MINECO) research grant (AGL2013-49159-C2-2- R). This research was also supported by CIBER -Consorcio Centro de Investigación Biomédica en Red- (CB 2021), Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea – NextGenerationEU. D. Jim´enez-Martín holds a Ph.D. contract granted by Own Research Plan of the University of Cordoba. Funding for open access charge: Universidad de Cordoba / CBUA.
DS RISalud
RD Apr 11, 2025