TY - JOUR AU - López de Silanes, Isabel AU - Gorospe, Myriam AU - Taniguchi, Hiroaki AU - Abdelmohsen, Kotb AU - Srikantan, Subramanya AU - Alaminos, Miguel AU - Berdasco, María AU - Urdinguio, Rocío G AU - Fraga, Mario F AU - Jacinto, Filipe V AU - Esteller, Manel PY - 2009 DO - 10.1093/nar/gkp123 SN - 0305-1048 UR - http://hdl.handle.net/10668/697 T2 - Nucleic acids research AB - The molecular basis underlying the aberrant DNA-methylation patterns in human cancer is largely unknown. Altered DNA methyltransferase (DNMT) activity is believed to contribute, as DNMT expression levels increase during tumorigenesis. Here, we present... LA - en PB - Oxford University Press KW - Antígenos de Superficie KW - Antineoplastic Agents KW - Secuencia de Bases KW - Línea Celular Tumoral KW - Cisplatino KW - ADN (Citosina-5-) Metiltransferasa KW - Metilación de ADN KW - Hu KW - Datos de Secuencia Molecular KW - Estabilidad del ARN KW - RNA, Messenger KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Base Sequence KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Chlorine Compounds::Cisplatin KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases::DNA Modification Methylases::DNA-Cytosine Methylases::DNA (Cytosine-5-)-Methyltransferase KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::DNA Methylation KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Information Science::Information Science::Information Services::Documentation::Molecular Sequence Data KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::RNA Stability KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Nucleoproteins::RNA-Binding Proteins KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Antigens::Antigens, Surface KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases::Protein Methyltransferases TI - The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA TY - research article ER -