TY  - JOUR
AU  - Lorenzo, Petra I
AU  - Martin Vazquez, Eugenia
AU  - López-Noriega, Livia
AU  - Fuente-Martín, Esther
AU  - Mellado-Gil, José M
AU  - Franco, Jaime M
AU  - Cobo-Vuilleumier, Nadia
AU  - Guerrero Martínez, José A
AU  - Romero-Zerbo, Silvana Y
AU  - Perez-Cabello, Jesús A
AU  - Rivero Canalejo, Sabrina
AU  - Campos-Caro, Antonio
AU  - Lachaud, Christian Claude
AU  - Crespo Barreda, Alejandra
AU  - Aguilar-Diosdado, Manuel
AU  - García Fuentes, Eduardo
AU  - Martin-Montalvo, Alejandro
AU  - Álvarez Dolado, Manuel
AU  - Martin, Franz
AU  - Rojo-Martinez, Gemma
AU  - Pozo, David
AU  - Bérmudez-Silva, Francisco J
AU  - Comaills, Valentine
AU  - Reyes, José C
AU  - Gauthier, Benoit R
PY  - 2021
DO  - 10.7150/thno.57237
UR  - https://hdl.handle.net/10668/25255
T2  - Theranostics
AB  - Rationale: We recently demonstrated that the 'Metabesity' factor HMG20A regulates islet beta-cell functional maturity and adaptation to physiological stress such as pregnancy and pre-diabetes. HMG20A also dictates central nervous system (CNS)...
LA  - en
KW  - HMG20A
KW  - ORY1001.
KW  - astrocytes
KW  - inflammation
KW  - metabesity
KW  - metabolism
KW  - Adipose Tissue
KW  - Adult
KW  - Animals
KW  - Astrocytes
KW  - Cell Survival
KW  - Co-Repressor Proteins
KW  - Diabetes Mellitus, Type 2
KW  - Diet, High-Fat
KW  - Glial Fibrillary Acidic Protein
KW  - Gliosis
KW  - Glucose
KW  - High Mobility Group Proteins
KW  - Histone Demethylases
KW  - Humans
KW  - Hypothalamus
KW  - Interleukin-1beta
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Middle Aged
KW  - Mitochondria
KW  - Nerve Tissue Proteins
KW  - Neurons
KW  - Obesity
KW  - RNA, Small Interfering
KW  - RNA-Seq
TI  - The metabesity factor HMG20A potentiates astrocyte survival and reactive astrogliosis preserving neuronal integrity.
TY  - research article
VL  - 11
ER  -