RT Journal Article
T1 Dosimetric impact of bladder filling on organs at risk with barium contrast in the small bowel for adjuvant vaginal cuff brachytherapy
A1 Salas Buzon, Maria del Carmen
A1 Gutierrez Bayard, Lucia
A1 Rodriguez Sanchez, Raquel
A1 Quinones Rodriguez, Luis Angel
A1 Sayago Gil, Sarah
A1 Munoz Higueras, Cristina
K1 endometrial cancer
K1 vaginal cuff brachytherapy
K1 small bowel
K1 bladder distention
K1 barium
K1 High-dose-rate
K1 American brachytherapy
K1 Endometrial cancer
K1 3-dimensional dosimetry
K1 Vault brachytherapy
K1 Guidelines
K1 Carcinoma
AB Purpose: The aim of this prospective study was to analyze dosimetric impact of modifying bladder filling on dose distribution in organs at risk (OARs) when using contrast in the small bowel of patients under adjuvant therapy with high-dose-rate vaginal cuff brachytherapy (HDR-VCB) for endometrial cancer.Material and methods: This research included 19 patients who underwent laparoscopic surgery. They were treated with HDR-VCB and 2.5-3.5 cm diameter cylinders. Two successive computerized tomography (CT) scans were performed, with empty bladder and with bladder filled with 180 cc of saline solution. Bladder, rectum, sigmoid, and small bowel were delineated as OARs. Oral barium contrast was used to clearly visualize small bowel loops. Prescription dose was 7 Gy. Dose-volume histograms were generated for each OAR, with full and empty bladder to compare doses received.Results: Bladder distension had no dosimetric impact on the bladder, rectum, or sigmoid, unlike the small bowel. With full bladder, mean minimum dose at 2 cc (D-2cc) was not significantly higher for full vs. empty bladder (5.56 vs. 5.06 Gy, p = 0.07), whereas there was a significant reduction in the small bowel (1.68 vs. 2.70 Gy, p
PB Termedia publishing house ltd
SN 1689-832X
YR 2021
FD 2021-01-01
LK https://hdl.handle.net/10668/25225
UL https://hdl.handle.net/10668/25225
LA en
DS RISalud
RD Apr 5, 2025