RT Journal Article
T1 Comorbidities in Patients With Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A Comparative Registries-Based Study.
A1 Rúa-Figueroa, Iñigo
A1 Fernández Castro, Mónica
A1 Andreu, José L
A1 Sanchez-Piedra, Carlos
A1 Martínez-Taboada, Víctor
A1 Olivé, Alejandro
A1 López-Longo, Javier
A1 Rosas, José
A1 Galindo, María
A1 Calvo-Alén, Jaime
A1 Fernández-Nebro, Antonio
A1 Alonso, Fernando
A1 Rodríguez-Lozano, Beatriz
A1 Alberto García Vadillo, Jesús
A1 Menor, Raúl
A1 Narváez, Francisco Javier
A1 Erausquin, Celia
A1 García-Aparicio, Ángel
A1 Tomero, Eva
A1 Manrique-Arija, Sara
A1 Horcada, Loreto
A1 Uriarte, Esther
A1 Gil, Susana
A1 Blanco, Ricardo
A1 López-González, Ruth
A1 Boteanu, Alina
A1 Freire, Mercedes
A1 Galisteo, Carlos
A1 Rodríguez-Gómez, Manuel
A1 Díez-Álvarez, Elvira
A1 Pego-Reigosa, José M
A1 Sjogrenser and Relesser Researchers and EAS-SER Group, 
AB To compare the prevalence of the main comorbidities in 2 large cohorts of patients with primary Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE), with a focus on cardiovascular (CV) diseases. This was a cross-sectional multicenter study where the prevalence of more relevant comorbidities in 2 cohorts was compared. Patients under followup from SJOGRENSER (Spanish Rheumatology Society Registry of Primary SS) and RELESSER (Spanish Rheumatology Society Registry of SLE), and who fulfilled the 2002 American-European Consensus Group and 1997 American College of Rheumatology classification criteria, respectively, were included. A binomial logistic regression analysis was carried out to explore potential differences, making general adjustments for age, sex, and disease duration and specific adjustments for each variable, including CV risk factors and treatments, when appropriate. A total of 437 primary SS patients (95% female) and 2,926 SLE patients (89% female) were included. The mean age was 58.6 years (interquartile range [IQR] 50.0-69.9 years) for primary SS patients and 45.1 years (IQR 36.4-56.3 years) for SLE patients (P  Primary SS patients have a consistently less serious CV comorbidity burden and a lower prevalence of severe infection than those with SLE. In contrast, their risk of lymphoma is greater.
YR 2016
FD 2016-11-21
LK http://hdl.handle.net/10668/10393
UL http://hdl.handle.net/10668/10393
LA en
DS RISalud
RD Mar 14, 2025