RT Journal Article
T1 Prevalence of Anxiety and Depression Symptoms and Their Relationship with Nutritional Status and Mortality in Patients with Colorectal Cancer.
A1 Soria-Utrilla, Virginia
A1 Sanchez-Torralvo, Francisco Jose
A1 Gonzalez-Poveda, Ivan
A1 Mera-Velasco, Santiago
A1 Porras, Nuria
A1 Toval-Mata, Jose Antonio
A1 Garcia-Olivares, Maria
A1 Ruiz-Lopez, Manuel
A1 Gonzalo-Marin, Montserrat
A1 Carrasco-Campos, Joaquin
A1 Tapia, Maria Jose
A1 Santoyo-Santoyo, Julio
A1 Olveira, Gabriel
K1 HADS
K1 Anxiety
K1 Cancer
K1 Colorectal
K1 Depression
K1 Malnutrition
K1 Oncology
AB Anxiety and depression are common in patients with cancer. The aim of this study is to determine the prevalence of anxiety and depression symptoms in colorectal cancer (CRC) patients awaiting elective surgery and whether there is an association with their preoperative nutritional status and postoperative mortality. A prospective study was conducted on 215 patients with CRC proposed for surgery. Data about nutritional status were collected using the Global Leadership Initiative on Malnutrition (GLIM) criteria, while anxiety and depression symptoms data were collected using Hospital Anxiety and Depression Scale (HADS). HADS detected possible anxiety in 41.9% of patients, probable anxiety in 25.6%, possible depression in 21.9%, and probable depression in 7.9%. GLIM criteria found 116 (53.9%) patients with malnutrition. The HADS score for depression subscale was significantly higher in malnourished patients than in well-nourished (5.61 ± 3.65 vs. 3.95 ± 2.68; p = 0.001). After controlling for potential confounders, malnourished patients were 10.19 times more likely to present probable depression (95% CI 1.13-92.24; p = 0.039). Mortality was 1.9%, 4,2%, and 5.6% during admission and after 6 and 12 months, respectively. Compared to patients without depressive symptomatology, in patients with probable depression, mortality risk was 14.67 times greater (95% CI 1.54-140.21; p = 0.02) during admission and 6.62 times greater (95% CI 1.34-32.61; p = 0.02) after 6 months. The presence of anxiety and depression symptoms in CRC patients awaiting elective surgery is high. There is an association between depression symptoms, preoperative nutritional status, and postoperative mortality.
PB MDPI
YR 2022
FD 2022-10-19
LK http://hdl.handle.net/10668/21115
UL http://hdl.handle.net/10668/21115
LA en
NO Soria-Utrilla V, Sánchez-Torralvo FJ, González-Poveda I, Mera-Velasco S, Porras N, Toval-Mata JA, et al. Prevalence of Anxiety and Depression Symptoms and Their Relationship with Nutritional Status and Mortality in Patients with Colorectal Cancer. Int J Environ Res Public Health. 2022 Oct 19;19(20):13548
DS RISalud
RD Aug 13, 2025