RT Journal Article T1 European interdisciplinary guideline on invasive squamous cell carcinoma of the skin: Part 1. epidemiology, diagnostics and prevention. A1 Stratigos, Alexander J A1 Garbe, Claus A1 Dessinioti, Clio A1 Lebbe, Celeste A1 Bataille, Veronique A1 Bastholt, Lars A1 Dreno, Brigitte A1 Fargnoli, Maria Concetta A1 Forsea, Ana Maria A1 Frenard, Cecille A1 Harwood, Catherine Α A1 Hauschild, Axel A1 Hoeller, Christoph A1 Kandolf-Sekulovic, Lidija A1 Kaufmann, R A1 Kelleners-Smeets, Nicole Wj A1 Malvehy, Josep A1 Del Marmol, Veronique A1 Middleton, Mark R A1 Moreno-Ramirez, David A1 Pellecani, Giovanni A1 Peris, Ketty A1 Saiag, Philippe A1 van den Beuken-van Everdingen, Marieke H J A1 Vieira, Ricardo A1 Zalaudek, Iris A1 Eggermont, Alexander M M A1 Grob, Jean-Jacques A1 European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organization for Research and Treatment of Cancer (EORTC) K1 Diagnosis K1 High-risk common primary cSCC K1 Imaging K1 Invasive cutaneous squamous cell carcinoma K1 Locally advanced Cscc K1 Low-risk K1 Metastatic cSCC K1 Prevention K1 Prognosis K1 Staging AB Invasive cutaneous squamous cell carcinoma (cSCC) is one of the most common cancers in the white populations, accounting for 20% of all cutaneous malignancies. Factors implicated in cSCC etiopathogenesis include ultraviolet radiation exposure and chronic photoaging, age, male sex, immunosuppression, smoking and genetic factors. A collaboration of multidisciplinary experts from the European Dermatology Forum (EDF), the European Association of Dermato-Oncology (EADO) and the European Organisation of Research and Treatment of Cancer (EORTC) was formed to update recommendations on cSCC classification, diagnosis, risk stratification, staging and prevention, based on current literature, staging systems and expert consensus. Common cSCCs are typically indolent tumors, and most have a good prognosis with 5-year cure rates of greater than 90%, and a low rate of metastases ( YR 2020 FD 2020-02-26 LK http://hdl.handle.net/10668/15183 UL http://hdl.handle.net/10668/15183 LA en DS RISalud RD Apr 15, 2025