TY - JOUR AU - Sánchez-Hernández, Sabina AU - Gutierrez-Guerrero, Alejandra AU - Martín-Guerra, Rocío AU - Cortijo-Gutierrez, Marina AU - Tristán-Manzano, María AU - Rodriguez-Perales, Sandra AU - Sanchez, Laura AU - Garcia-Perez, Jose Luis AU - Chato-Astrain, Jesus AU - Fernandez-Valades, Ricardo AU - Carrillo-Galvez, Ana Belén AU - Anderson, Per AU - Montes, Rosa AU - Real, Pedro J AU - Martin, Francisco AU - Benabdellah, Karim PY - 2018 DO - 10.1016/j.omtn.2018.08.007 SN - 2162-2531 UR - http://hdl.handle.net/10668/12961 T2 - Molecular therapy. Nucleic acids AB - Integration-defective lentiviral vectors (IDLVs) have become an important alternative tool for gene therapy applications and basic research. Unfortunately, IDLVs show lower transgene expression as compared to their integrating counterparts. In this... LA - en KW - HS4 insulator KW - IDLV KW - gene therapy KW - lentiviral vector KW - scaffold or matrix attachment regions TI - The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes. TY - research article VL - 13 ER -