RT Journal Article
T1 Age-dependent effect of metabolic phenotypes on carotid atherosclerotic disease in coronary heart disease patients (CORDIOPREV study).
A1 Gutierrez-Mariscal, Francisco M
A1 Garcia-Rios, Antonio
A1 Gomez-Luna, Purificacion
A1 Fernandez-Gandara, Carolina
A1 Cardelo, Magdalena P
A1 de la Cruz-Ares, Silvia
A1 Rodriguez-Cantalejo, Fernando
A1 Luque, Raul M
A1 Leon-Acuña, Ana
A1 Delgado-Lista, Javier
A1 Perez-Martinez, Pablo
A1 Yubero-Serrano, Elena M
A1 Lopez-Miranda, Jose
K1 Cardiovascular risk factors
K1 Carotid atherosclerosis
K1 Metabolic flexibility
K1 Metabolically healthy obese
AB Aging is associated with a high risk for cardiovascular disease. The relation of obesity and risk of cardiovascular events appears to be more closely linked to certain clinical or metabolic phenotypes than to obesity itself. Our aim was to establish whether aging influenced the metabolic phenotypes regarding to cardiovascular risk, evaluated by changes in the intima media thickness-common carotid (IMT-CC), in coronary heart disease (CHD) patients. In this cross-sectional study, 1002 CHD patients were studied at entry from the CORDIOPREV study. We performed carotid ultrasound assessment to obtain their IMT-CC values. Carotid atherosclerosis was considered to exist if IMT-CC > 0.7 mm. Age determined a higher IMT-CC, regardless metabolic phenotype (all p  Our results suggest that CHD patients aged≥60 are less metabolic flexible compared to patients aged
PB BioMed Central Ltd.
YR 2020
FD 2020-04-01
LK http://hdl.handle.net/10668/15414
UL http://hdl.handle.net/10668/15414
LA en
NO Gutierrez-Mariscal FM, García-Ríos A, Gómez-Luna P, Fernández-Gandara C, Cardelo MP, de la Cruz-Ares S, et al. Age-dependent effect of metabolic phenotypes on carotid atherosclerotic disease in coronary heart disease patients (CORDIOPREV study). BMC Geriatr. 2020 Apr 22;20(1):151.
NO We would like to thank the EASP (Escuela Andaluza de Salud Publica), Granada (Spain), for carrying out the randomization process in this study. The CIBEROBN is an initiative of the Instituto de Salud Carlos III, Madrid, Spain.
DS RISalud
RD Apr 9, 2025