TY  - JOUR
AU  - Wu, Xi-Xi
AU  - Zheng, Kenneth I
AU  - Boursier, Jerome
AU  - Wah-Kheong, Chan
AU  - Yilmaz, Yusuf
AU  - Romero-Gomez, Manuel
AU  - El-Kassas, Mohamed
AU  - Targher, Giovanni
AU  - Byrne, Christopher D
AU  - Huang, Zhi-Ming
AU  - Zheng, Ming-Hua
PY  - 2021
DO  - 10.1016/j.eclinm.2021.101145
UR  - https://hdl.handle.net/10668/27477
T2  - EClinicalMedicine
AB  - There is an unmet need for non-invasive biomarkers for the diagnosis of nonalcoholic steatohepatitis (NASH) in non-specialized settings. We aimed to develop and validate a non-invasive test for diagnosing NASH in individuals with biopsy-proven...
LA  - en
PB  - The Lancet Publishing Group
KW  - ALT, alanine aminotransferase
KW  - AST, aspartate aminotransferase
KW  - AUROC, area under receiver operating characteristics
KW  - BMI, body mass index
KW  - CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration
KW  - CRN, Clinical Research Network
KW  - GAA, guanidine-acetic acid
KW  - HBV, chronic viral hepatitis B
KW  - HCV, chronic viral hepatitis C
KW  - NAFLD, nonalcoholic fatty liver disease
KW  - NAS, NAFLD Activity Score
KW  - NASH, nonalcoholic steatohepatitis
KW  - NPV, negative predictive value
KW  - Nonalcoholic steatohepatitis
KW  - PERSONS, Prospective Epidemic Research Specifically Of NASH
KW  - PPV, positive predictive value
KW  - SCr, serum creatinine
KW  - Se, sensitivity
KW  - Sp, specificity
KW  - T2DM, type 2 diabetes mellitus
KW  - e-GFR, estimated glomerular filtration rate
KW  - metabolic dysfunction-associated fatty liver disease
KW  - nonalcoholic fatty liver disease
KW  - primary care
KW  - scoring system
KW  - screening
KW  - Non-alcoholic Fatty Liver Disease
KW  - Predictive Value of Tests
KW  - Creatinine
KW  - ROC Curve
KW  - Diabetes Mellitus
KW  - Aspartate Aminotransferases
KW  - Biopsy
KW  - Inflammation
KW  - Biomarkers
TI  - acNASH index to diagnose nonalcoholic steatohepatitis: a prospective derivation and global validation study.
TY  - research article
VL  - 41
ER  -