RT Journal Article
T1 Identification of a Strigoterpenoid with Dual Nrf2 and Nf-κB Modulatory Activity.
A1 Rogati, Federica
A1 Millán, Estrella
A1 Appendino, Giovanni
A1 Correa, Alejandro
A1 Caprioglio, Diego
A1 Minassi, Alberto
A1 Muñoz, Eduardo
AB The sesquiterpene-coumarin ether samarcandone provided a suitable framework to replace the apocarotenoid A-C ring system of strigol (1), replicating, after linking to a butenolide moiety, the activity of the natural phytohormone on Nrf2 and also showing potent NF-kB inhibitory activity, overall modulating two critical pathways of inflammation and cancer.
SN 1948-5875
YR 2019
FD 2019-01-08
LK https://hdl.handle.net/10668/28272
UL https://hdl.handle.net/10668/28272
LA en
DS RISalud
RD Apr 10, 2025