TY - JOUR AU - Smith, Matthew R AU - Saad, Fred AU - Chowdhury, Simon AU - Oudard, Stéphane AU - Hadaschik, Boris A AU - Graff, Julie N AU - Olmos, David AU - Mainwaring, Paul N AU - Lee, Ji Youl AU - Uemura, Hiroji AU - De Porre, Peter AU - Smith, Andressa A AU - Brookman-May, Sabine D AU - Li, Susan AU - Zhang, Ke AU - Rooney, Brendan AU - Lopez-Gitlitz, Angela AU - Small, Eric J PY - 2020 DO - 10.1016/j.eururo.2020.08.011 UR - http://hdl.handle.net/10668/16238 T2 - European urology AB - The phase 3 SPARTAN study evaluated apalutamide versus placebo in patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) and prostate-specific antigen doubling time of ≤10 mo. At primary analysis, apalutamide improved median... LA - en KW - Apalutamide KW - Nonmetastatic castration-resistant prostate cancer KW - Overall survival KW - Subsequent therapy KW - Time to cytotoxic chemotherapy KW - Aged KW - Cross-Over Studies KW - Humans KW - Male KW - Middle Aged KW - Prostatic Neoplasms, Castration-Resistant KW - Survival Rate KW - Thiohydantoins TI - Apalutamide and Overall Survival in Prostate Cancer. TY - research article VL - 79 ER -