RT Journal Article
T1 Analysis of macular and nerve fiber layer thickness in multiple sclerosis patients according to severity level and optic neuritis episodes
A1 Soler Garcia, A.
A1 Padilla Parrado, F.
A1 Figueroa-Ortiz, L. C.
A1 Gonzalez Gomez, A.
A1 Garcia-Ben, A.
A1 Garcia-Ben, E.
A1 Garcia-Campos, J. M.
K1 Macular thickness
K1 Nerve fibre layer
K1 Multiple sclerosis
K1 Expanded disability status scale
K1 Optic neuritis
K1 Coherence tomography
K1 Brain atrophy
K1 Disability
AB Introduction: Quantitative assessment of macular and nerve fibre layer thickness in multiple sclerosis patients with regard to expanded disability status scale (EDSS) and presence or absence of previous optic neuritis episodes.Methods: We recruited 62 patients with multiple sclerosis (53 relapsing-remitting and 9 secondary progressive) and 12 disease-free controls. All patients underwent an ophthalmological examination, including quantitative analysis of the nerve fibre layer and macular thickness using optical coherence tomography. Patients were classified according to EDSS as A (lower than 1.5), B (between 1.5 and 3.5), and C (above 3.5).Results: Mean nerve fibre layer thickness in control, A, B, and C groups was 103.35 +/- 12.62, 99.04 +/- 14.35, 93.59 +/- 15.41, and 87.36 +/- 18.75 mu m respectively, with statistically significant differences (P
PB Elsevier espana slu
SN 0213-4853
YR 2016
FD 2016-07-01
LK http://hdl.handle.net/10668/18850
UL http://hdl.handle.net/10668/18850
LA es
DS RISalud
RD Apr 10, 2025