TY - JOUR AU - Hadjihambi, Anna AU - Harrison, Ian F AU - Costas-Rodríguez, Marta AU - Vanhaecke, Frank AU - Arias, Natalia AU - Gallego-Durán, Rocío AU - Mastitskaya, Svetlana AU - Hosford, Patrick S AU - Olde Damink, Steven W M AU - Davies, Nathan AU - Habtesion, Abeba AU - Lythgoe, Mark F AU - Gourine, Alexander V AU - Jalan, Rajiv PY - 2018 DO - 10.1016/j.jhep.2018.08.021 UR - http://hdl.handle.net/10668/12929 T2 - Journal of hepatology AB - Neuronal function is exquisitely sensitive to alterations in the extracellular environment. In patients with hepatic encephalopathy (HE), accumulation of metabolic waste products and noxious substances in the interstitial fluid of the brain is thought... LA - en KW - Cirrhosis KW - Glymphatic system KW - Hepatic encephalopathy KW - MRI KW - Mass spectrometry KW - Animals KW - Aquaporin 4 KW - Brain KW - Cerebrospinal Fluid KW - Disease Models, Animal KW - Glymphatic System KW - Hepatic Encephalopathy KW - Intracranial Pressure KW - Magnetic Resonance Imaging KW - Male KW - Rats KW - Rats, Sprague-Dawley TI - Impaired brain glymphatic flow in experimental hepatic encephalopathy. TY - research article VL - 70 ER -