TY - JOUR AU - del Rio, Maria-Luisa AU - Fernandez-Renedo, Carlos AU - Chaloin, Olivier AU - Scheu, Stefanie AU - Pfeffer, Klaus AU - Shintani, Yasushi AU - Perez-Simon, Jose-Antonio AU - Schneider, Pascal AU - Rodriguez-Barbosa, Jose-Ignacio PY - 2016 DO - 10.1080/19420862.2015.1132130 UR - http://hdl.handle.net/10668/9722 T2 - mAbs AB - Tumor necrosis factor (TNF)/TNF receptor (TNFR) superfamily members play essential roles in the development of the different phases of the immune response. Mouse LIGHT (TNFSF14) is a type II transmembrane protein with a C-terminus extracellular TNF... LA - en KW - Alloreactivity KW - CD258) KW - CD270) KW - DcR3 (TNFRSF6b) KW - HVEM (TNFRSF14 KW - LIGHT (TNFSF14 KW - LTβR (TNFRSF3) KW - co-stimulation KW - cytotoxicity KW - graft rejection KW - graft-vs.-host disease KW - transplantation KW - Adoptive Transfer KW - Animals KW - CD8-Positive T-Lymphocytes KW - Cell Proliferation KW - Mice KW - Mice, Inbred BALB C KW - Mice, Knockout KW - Receptors, Interleukin-7 KW - Signal Transduction KW - Tumor Necrosis Factor Ligand Superfamily Member 14 TI - Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells. TY - research article VL - 8 ER -