TY - JOUR AU - Garcia-Carbonero, Rocio AU - Salazar, Ramon AU - Duran, Ignacio AU - Osman-Garcia, Ignacio AU - Paz-Ares, Luis AU - Bozada, Juan M AU - Boni, Valentina AU - Blanc, Christine AU - Seymour, Len AU - Beadle, John AU - Alvis, Simon AU - Champion, Brian AU - Calvo, Emiliano AU - Fisher, Kerry PY - 2017 DO - 10.1186/s40425-017-0277-7 UR - http://hdl.handle.net/10668/11588 T2 - Journal for immunotherapy of cancer AB - Enadenotucirev (formerly ColoAd1) is a tumor-selective chimeric adenovirus with demonstrated preclinical activity. This phase 1 Mechanism of Action study assessed intravenous (IV) delivery of enadenotucirev in patients with resectable colorectal... LA - en KW - Adenoviruses, Human KW - Administration, Intravenous KW - CD8-Positive T-Lymphocytes KW - Carcinoma, Non-Small-Cell Lung KW - Carcinoma, Renal Cell KW - Carcinoma, Transitional Cell KW - Colorectal Neoplasms KW - Combined Modality Therapy KW - DNA, Viral KW - Digestive System Surgical Procedures KW - Humans KW - Lung Neoplasms KW - Oncolytic Virotherapy KW - Oncolytic Viruses KW - Pulmonary Surgical Procedures KW - Treatment Outcome KW - Urologic Surgical Procedures TI - Phase 1 study of intravenous administration of the chimeric adenovirus enadenotucirev in patients undergoing primary tumor resection. TY - research article VL - 5 ER -