TY  - JOUR
AU  - Muñoz, Miguel
AU  - Coveñas, Rafael
PY  - 2020
DO  - 10.3390/cancers12092682
UR  - http://hdl.handle.net/10668/3686
T2  - Cancers
AB  - Neurokinin-1 receptor (NK-1R) antagonists exert antitumor action, are safe and do not cause serious side-effects. These antagonists (via the NK-1R) exert multiple actions against cancer: antiproliferative and anti-Warburg effects and apoptotic,...
LA  - en
PB  - MDPI
KW  - Apoptosis
KW  - Antitumor
KW  - Antimetastasis
KW  - Anti-angiogenesis
KW  - NK-1 receptor
KW  - Substance P
KW  - Drug repositioning
KW  - Emend
KW  - Antineoplásicos
KW  - Genes Supresores de Tumor
KW  - Inhibidores de la angiogénesis
KW  - Receptores de neuroquinina-1
KW  - Sustancia P
KW  - Reposicionamiento de medicamentos
KW  - Aprepitant
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death::Apoptosis
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Neoplasm::Genes, Tumor Suppressor
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Growth Inhibitors::Angiogenesis Inhibitors
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Neurotransmitter::Receptors, Neuropeptide::Receptors, Tachykinin::Receptors, Neurokinin-1
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Neuropeptides::Tachykinins::Substance P
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning
TI  - The Neurokinin-1 Receptor Antagonist Aprepitant: An Intelligent Bullet against Cancer?
TY  - review article
ER  -