RT Journal Article T1 Associations of dietary energy density with body composition and cardiometabolic risk in children with overweight and obesity: role of energy density calculations, under-reporting energy intake and physical activity. A1 Gomez-Bruton, Alejandro A1 Arenaza, Lide A1 Medrano, Maria A1 Mora-Gonzalez, Jose A1 Cadenas-Sanchez, Cristina A1 Migueles, Jairo H A1 Muñoz-Hernández, Victoria A1 Merchan-Ramirez, Elisa A1 Martinez-Avila, Wendy Daniela A1 Maldonado, Jose A1 Oses, Maddi A1 Tobalina, Ignacio A1 Gracia-Marco, Luis A1 Vicente-Rodriguez, German A1 Ortega, Francisco B A1 Labayen, Idoia K1 BF% body fat percentage K1 DXA dual-energy X-ray absorptiometry K1 ED energy density K1 EDS energy density from solid K1 EDSL energy density from solid plus liquids K1 EI energy intake K1 FMI fat mass index K1 MVPA moderate to vigorous physical activity K1 Adiposity K1 Childhood K1 Diet K1 Dual-energy X-ray absorptiometry K1 Moderate to vigorous physical activity K1 Nutrition AB This study examined (1) the association of dietary energy density from solid (EDS) and solid plus liquids (EDSL) with adiposity and cardiometabolic risk factors (CRF) in children with overweight and obesity, (2) the effect of under-reporting on the mentioned associations and (3) whether the association between ED and body composition and CRF is influenced by levels of physical activity. In a cross-sectional design, 208 overweight and obese children (8-12-year-old; 111 boys) completed two non-consecutive 24 h recalls. ED was calculated using two different approaches: EDS and EDSL. Under-reporters were determined with the Goldberg method. Body composition, anthropometry and fasting blood sample measurements were performed. Moderate to vigorous physical activity (MVPA) was registered with accelerometers (7-d-register). Linear regressions were performed to evaluate the association of ED with the previously mentioned variables. Neither EDS nor EDSL were associated with body composition or CRF. However, when under-reporters were excluded, EDS was positively associated with BMI (P=0·019), body fat percentage (P=0·005), abdominal fat (P=0·008) and fat mass index (P=0·018), while EDSL was positively associated with body fat percentage (P=0·008) and fat mass index (P=0·026). When stratifying the group according to physical activity recommendations, the aforementioned associations were only maintained for non-compliers. Cluster analysis showed that the low-ED and high-MVPA group presented the healthiest profile for all adiposity and CRF. These findings could partly explain inconsistencies in literature, as we found that different ED calculations entail distinct results. Physical activity levels and excluding under-reporters greatly influence the associations between ED and adiposity in children with overweight and obesity. PB Cambridge University Press YR 2019 FD 2019-01-27 LK http://hdl.handle.net/10668/13521 UL http://hdl.handle.net/10668/13521 LA en NO Gomez-Bruton A, Arenaza L, Medrano M, Mora-Gonzalez J, Cadenas-Sanchez C, Migueles JH, et al. Associations of dietary energy density with body composition and cardiometabolic risk in children with overweight and obesity: role of energy density calculations, under-reporting energy intake and physical activity. Br J Nutr. 2019 May;121(9):1057-1068. DS RISalud RD Apr 14, 2025