TY - JOUR AU - Navarrete, Carmen AU - Carrillo-Salinas, Francisco AU - Palomares, Belen AU - Mecha, Miriam AU - Jimenez-Jimenez, Carla AU - Mestre, Leyre AU - Feliu, Ana AU - Bellido, Maria L AU - Fiebich, Bernd L AU - Appendino, Giovanni AU - Calzado, Marco A AU - Guaza, Carmen AU - Muñoz, Eduardo PY - 2018 DO - 10.1186/s12974-018-1103-y UR - http://hdl.handle.net/10668/12198 T2 - Journal of neuroinflammation AB - Multiple sclerosis (MS) is characterized by a combination of inflammatory and neurodegenerative processes variously dominant in different stages of the disease. Thus, immunosuppression is the goal standard for the inflammatory stage, and novel... LA - en PB - BioMed Central KW - Arginase 1 KW - Cannabinoids KW - EPO KW - HIF-1α KW - Multiple sclerosis KW - PHDs KW - VEGF KW - Animals KW - Arginase KW - Cell hypoxia KW - Cell line, transformed KW - Cell movement KW - Cell polarity KW - Cytokines KW - Disease models, animal KW - Encephalomyelitis, autoimmune, experimental KW - Endothelial cells KW - Female KW - Gene expression regulation KW - Humans KW - Macrophages KW - Male KW - Mice KW - Mice, inbred C57BL KW - Microglia KW - Neovascularization, pathologic KW - Quinones KW - Receptor, cannabinoid, CB2 TI - Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy. TY - research article VL - 15 ER -