TY  - JOUR
AU  - Prados, Maria E
AU  - Correa-Saez, Alejandro
AU  - Unciti-Broceta, Juan D
AU  - Garrido-Rodriguez, Martin
AU  - Jimenez-Jimenez, Carla
AU  - Mazzone, Massimiliano
AU  - Minassi, Alberto
AU  - Appendino, Giovanni
AU  - Calzado, Marco A
AU  - Muñoz, Eduardo
PY  - 2021
DO  - 10.1007/s13311-021-01089-4
UR  - http://hdl.handle.net/10668/18281
T2  - Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
AB  - Huntington's disease (HD) is a neurodegenerative disorder characterized by unwanted choreatic movements, behavioral and psychiatric disturbances, and dementia. The activation of the hypoxic response pathway through the pharmacological inhibition of...
LA  - en
PB  - Elsevier
KW  - Betulinic acid
KW  - Hypoxia-inducing factor
KW  - Neuroprotection
KW  - Prolyl-hydroxylases
KW  - Protein phosphatase A2
KW  - Animals
KW  - Corpus striatum
KW  - HEK293 cells
KW  - Humans
KW  - Hypoxia-inducible factor 1, alpha subunit
KW  - Hypoxia-inducible factor-proline dioxygenases
KW  - Mice
KW  - Mice, inbred C57BL
KW  - NIH 3T3 cells
KW  - Neuroprotective agents
KW  - Nitro compounds
KW  - Pentacyclic triterpenes
KW  - Phosphorylation
KW  - Propionates
KW  - Protein phosphatase 2
KW  - Betulinic acid
TI  - Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2.
TY  - research article
VL  - 18
ER  -