RT Generic T1 Physical Activity Promotion Programmes in Childhood Cancer Patients and Their Impact on Fatigue and Pain: A Systematic Review A1 Malysse, Catherine A1 Romero-Galisteo, Rita Pilar A1 Merchan-Baeza, Jose Antonio A1 Duran-Millan, J. Ignacio A1 Gonzalez-Sanchez, Manuel A1 Galan-Mercant, Alejandro K1 child K1 cancer K1 fatigue K1 pain K1 health promotion K1 physical activity K1 coaching AB Cancer is one of the main causes of death in children, however, the techniques and interventions applied allow the cure of 80% of diagnosed cases. The aim of this review was to determine the benefits of a health and physical activity promotion programme to reduce pain and fatigue symptoms in children and adolescents with cancer. The databases PubMed, Embase, Scopus, Cochrane, Web of Science and PEDro were searched between December 2020 and January 2021 to elaborate this review, using the keywords child, cancer, exercise, fatigue and pain. The review was preregistered in PROSPERO (ID CRD42021262183). Six studies, out of 937 identified at baseline, were finally included in the review: four randomised controlled trials and two quasi-experimental studies. The total sample size of all the included studies was of 474 participants with very different types of cancer and evolution, and outcome variables were pain, fatigue, physical activity level, self-efficacy and quality of life. A health and physical activity promotion programme seems to improve fatigue in paediatric cancer patients and survivors, but no significant results were found related to pain. PB Mdpi SN 2227-9067 YR 2021 FD 2021-12-02 LK https://hdl.handle.net/10668/25249 UL https://hdl.handle.net/10668/25249 LA en NO Malysse C, Romero-Galisteo RP, Merchán-Baeza JA, Durán-Millán JI, González-Sánchez M, Galan-Mercant A. Physical Activity Promotion Programmes in Childhood Cancer Patients and Their Impact on Fatigue and Pain: A Systematic Review. Children (Basel). 2021;8(12):1119. Published 2021 Dec 2. NO This research and the APC was partial funded by the Erasmus+ Strategic Partnership for Higher Education Program (Key Action 203), grant number 2018-1-PL01-KA203-051055. DS RISalud RD Aug 8, 2025