TY - JOUR AU - Parra-Perez, Alberto M AU - Pérez-Jiménez, Amalia AU - Gris-Cárdenas, Isabel AU - Bonel-Pérez, Gloria C AU - Carrasco-Díaz, Luis M AU - Mokhtari, Khalida AU - García-Salguero, Leticia AU - Lupiáñez, José A AU - Rufino-Palomares, Eva E PY - 2022 DO - 10.3390/ijms23137053 UR - http://hdl.handle.net/10668/21171 T2 - International journal of molecular sciences AB - Hydroxytyrosol (HT), the main representative of polyphenols of olive oil, has been described as one of the most powerful natural antioxidants, also showing anti-inflammatory, antimicrobial, cardioprotective and anticancer activity in different type of... LA - en KW - HSP60 KW - PI3K/AKT signaling pathway KW - ROS level KW - apoptosis KW - cell cycle arrest KW - hydroxytyrosol KW - inflammation KW - leukemia cells KW - Animals KW - Anti-Inflammatory Agents KW - Apoptosis KW - Chaperonin 60 KW - Humans KW - Inflammation KW - Mice KW - Olea KW - Phenylethyl Alcohol KW - Phosphatidylinositol 3-Kinases KW - Polyphenols KW - Proto-Oncogene Proteins c-akt KW - Signal Transduction TI - Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity. TY - research article VL - 23 ER -