TY - JOUR AU - Martínez-Delgado, Paula AU - Lacerenza, Serena AU - Obrador-Hevia, Antonia AU - Lopez-Alvarez, Maria AU - Mondaza-Hernandez, José L. AU - Blanco-Alcaina, Elena AU - Sanchez-Bustos, Paloma AU - Hindi, Nadia AU - Moura, David S. AU - Martin-Broto, Javier PY - 2020 DO - 10.3390/cells9061449 UR - http://hdl.handle.net/10668/3711 T2 - Cells AB - Soft tissue sarcomas (STS) are a rare group of mesenchymal solid tumors with heterogeneous genetic profiles and clinical features. Systemic chemotherapy is the backbone treatment for advanced STS; however, STS frequently acquire resistance to standard... LA - en PB - MDPI KW - Cancer stem cells KW - Tumor-initiating cells KW - Soft-tissue sarcoma KW - Chemotherapy resistance KW - Stemness KW - Tumor heterogeneity KW - Genetic and epigenetic plasticity KW - Células madre neoplásicas KW - Sarcoma KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue::Sarcoma KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Drug Resistance::Drug Resistance, Neoplasm KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Neoplastic Processes::Carcinogenesis KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype TI - Cancer Stem Cells in Soft-Tissue Sarcomas TY - review article ER -