TY - JOUR AU - MacLennan, Marie AU - Garcia-Canadas, Marta AU - Reichmann, Judith AU - Khazina, Elena AU - Wagner, Gabriele AU - Playfoot, Christopher J. AU - Salvador-Palomeque, Carmen AU - Mann, Abigail R. AU - Peressini, Paula AU - Sanchez, Laura AU - Dobie, Karen AU - Read, David AU - Hung, Chao-Chun AU - Eskeland, Ragnhild AU - Meehan, Richard R. AU - Weichenrieder, Oliver AU - Luis Garcia-Perez, Jose AU - Adams, Ian R. PY - 2017 DO - 10.7554/eLife.26152 SN - 2050-084X UR - http://hdl.handle.net/10668/19396 T2 - Elife AB - Mobilization of retrotransposons to new genomic locations is a significant driver of mammalian genome evolution, but these mutagenic events can also cause genetic disorders. In humans, retrotransposon mobilization is mediated primarily by proteins... LA - en PB - Elife sciences publications ltd KW - High-frequency retrotransposition KW - Human l1 retrotransposition KW - Piwi-interacting rnas KW - End rule pathway KW - Ubiquitin ligase KW - Dna methylation KW - Orf1 protein KW - Transposable elements KW - Chaperone activity KW - Binding protein TI - Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells TY - research article VL - 6 ER -