TY  - JOUR
AU  - Kalincik, Tomas
AU  - Spelman, Timothy
AU  - Trojano, Maria
AU  - Duquette, Pierre
AU  - Izquierdo, Guillermo
AU  - Grammond, Pierre
AU  - Lugaresi, Alessandra
AU  - Hupperts, Raymond
AU  - Cristiano, Edgardo
AU  - Van Pesch, Vincent
AU  - Grand'Maison, Francois
AU  - La Spitaleri, Daniele
AU  - Rio, Maria Edite
AU  - Flechter, Sholmo
AU  - Oreja-Guevara, Celia
AU  - Giuliani, Giorgio
AU  - Savino, Aldo
AU  - Amato, Maria Pia
AU  - Petersen, Thor
AU  - Fernandez-Bolanos, Ricardo
AU  - Bergamaschi, Roberto
AU  - Iuliano, Gerardo
AU  - Boz, Cavit
AU  - Lechner-Scott, Jeannette
AU  - Deri, Norma
AU  - Gray, Orla
AU  - Verheul, Freek
AU  - Fiol, Marcela
AU  - Barnett, Michael
AU  - van Munster, Erik
AU  - Santiago, Vetere
AU  - Moore, Fraser
AU  - Slee, Mark
AU  - Saladino, Maria Laura
AU  - Alroughani, Raed
AU  - Shaw, Cameron
AU  - Kasa, Krisztian
AU  - Petkovska-Boskova, Tatjana
AU  - den Braber-Moerland, Leontien
AU  - Chapman, Joab
AU  - Skromne, Eli
AU  - Herbert, Joseph
AU  - Poehlau, Dieter
AU  - Needham, Merrilee
AU  - Bacile Bacile, Elizabeth Alejandra
AU  - Arruda, Walter Oleschko
AU  - Paine, Mark
AU  - Singhal, Bhim
AU  - Vucic, Steve
AU  - Cabrera-Gomez, Jose Antonio
AU  - Butzkueven, Helmut
PY  - 2013
DO  - 10.1371/journal.pone.0063480
UR  - http://hdl.handle.net/10668/2930
T2  - PloS One
AB  - OBJECTIVESTo compare treatment persistence between two dosages of interferon β-1a in a large observational multiple sclerosis registry and assess disease outcomes of first line MS treatment at these dosages using propensity scoring to adjust for...
LA  - en
PB  - Public Library of Science
KW  - Interferón beta
KW  - Relación dosis-respuesta a droga
KW  - Inyecciones subcutáneas
KW  - Funciones de verosimilitud
KW  - Esclerosis múltiple
KW  - Espectroscopía de resonancia magnética
KW  - Reproducibilidad de los resultados
KW  - Resultado del tratamiento
KW  - Privación del tratamiento
KW  - Adulto
KW  - Esclerosis múltiple
KW  - Cumplimiento y adherencia al tratamiento
KW  - Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Pharmacological Phenomena::Dose-Response Relationship, Drug
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Schedule
KW  - Medical Subject Headings::Check Tags::Female
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Injections::Injections, Subcutaneous
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Interferons::Interferon Type I::Interferon-beta
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis::Kaplan-Meier Estimate
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models, Statistical::Likelihood Functions
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Magnetic Resonance Imaging
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Health Behavior::Patient Compliance::Medication Adherence
KW  - Medical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Propensity Score
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Withholding Treatment
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
TI  - Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis.
TY  - research article
ER  -