RT Journal Article
T1 Impact of MELD Allocation System on Waiting List and Early Post-Liver Transplant Mortality.
A1 Jurado-Garcia, Juan
A1 Muñoz Garcia-Borruel, Maria
A1 Rodriguez-Peralvarez, Manuel Luis
A1 Ruiz-Cuesta, Patricia
A1 Poyato-Gonzalez, Antonio
A1 Barrera-Baena, Pilar
A1 Fraga-Rivas, Enrique
A1 Costan-Rodero, Guadalupe
A1 Briceño-Delgado, Javier
A1 Montero-Alvarez, Jose Luis
A1 de la Mata-Garcia, Manuel
K1 Carcinoma, hepatocellular
K1 Hepatic insufficiency
K1 Liver cirrhosis
K1 Liver neoplasms
K1 Liver transplantation
AB MELD allocation system has changed the clinical consequences on waiting list (WL) for LT, but its impact on mortality has been seldom studied. We aimed to assess the ability of MELD and other prognostic scores to predict mortality after LT. 301 consecutive patients enlisted for LT were included, and prioritized within WL by using the MELD-score according to: hepatic insufficiency (HI), refractory ascites (RA) and hepatocellular carcinoma (HCC). The analysis was performed to predict early mortality after LT (8 weeks). Patients were enlisted as HI (44.9%), RA (19.3%) and HCC (35.9%). The major aetiologies of liver disease were HCV (45.5%). Ninety-four patients (31.3%) were excluded from WL, with no differences among the three groups (p = 0.23). The remaining 207 patients (68.7%) underwent LT, being HI the most frequent indication (42.5%). HI patients had the shortest length within WL (113.6 days vs 215.8 and 308.9 respectively; p Patients enlisted due to HI had the highest early post-LT mortality rates despite of the shortest length within WL. The iMELD had the best accuracy to predict early post-LT mortality in patients with HI, and thus it may benefit the WL management.
PB Public Library of Science
YR 2016
FD 2016-05-04
LK http://hdl.handle.net/10668/10176
UL http://hdl.handle.net/10668/10176
LA en
NO Jurado-García J, Muñoz García-Borruel M, Rodríguez-Perálvarez ML, Ruíz-Cuesta P, Poyato-González A, Barrera-Baena P, et al. Impact of MELD Allocation System on Waiting List and Early Post-Liver Transplant Mortality. PLoS One. 2016 Jun 14;11(6):e0155822
DS RISalud
RD Apr 7, 2025