RT Journal Article
T1 Differential Diagnosis of Hepatic Mass with Central Scar: Focal Nodular Hyperplasia Mimicking Fibrolamellar Hepatocellular Carcinoma.
A1 Rudolphi-Solero, Teodoro
A1 Triviño-Ibáñez, Eva María
A1 Medina-Benítez, Antonio
A1 Fernández-Fernández, Javier
A1 Rivas-Navas, Daniel José
A1 Pérez-Alonso, Alejandro José
A1 Gómez-Río, Manuel
A1 Aroui-Luquin, Tarik
A1 Rodríguez-Fernández, Antonio
K1 central scar hepatic mass
K1 deshydroxy-(18F) fluorocholine
K1 fibrolamellar hepatocellular carcinoma
K1 focal nodular hyperplasia
K1 positron emission tomography
AB Fibrolamellar hepatocellular carcinoma is a primary hepatic tumor that usually appears in young adults. Radical surgery is considered curative for this kind of tumor, so early diagnosis becomes essential for the prognosis of the patients. The main characteristic of this entity is the central scar, which is the center of differential diagnosis. We report the case of a 30-year-old man who was diagnosed with fibrolamellar hepatocellular carcinoma by ultrasonography. Contrast-enhanced CT confirmed this diagnosis, and the patient underwent a [18F] fluorocholine PET/CT. Hypermetabolism and the morphology in the nuclear medicine exploration suggest neoplastic nature of the lesion. Radical surgery was performed, and histopathologic analysis was performed, which resulted in focal nodular hyperplasia. Hepatic masses with central scar could have a difficult differential diagnosis, and focal nodular hyperplasia could mimic fibrolamellar hepatocellular carcinoma imaging patterns. These morphofunctional characteristics have not been described in [18F] Fluorocholine PET/CT, so there is a need to find out the potential role PET/CT in the differential diagnosis of hepatic mass with central scar.
SN 2075-4418
YR 2021
FD 2021-12-27
LK http://hdl.handle.net/10668/20954
UL http://hdl.handle.net/10668/20954
LA en
DS RISalud
RD Apr 10, 2025