RT Journal Article T1 Implications of ACC/AHA Versus ESC/EAS LDL-C Recommendations for Residual Risk Reduction in ASCVD: A Simulation Study From DA VINCI. A1 Vallejo-Vaz, Antonio J A1 Bray, Sarah A1 Villa, Guillermo A1 Brandts, Julia A1 Kiru, Gaia A1 Murphy, Jennifer A1 Banach, Maciej A1 De Servi, Stefano A1 Gaita, Dan A1 Gouni-Berthold, Ioanna A1 Kees Hovingh, G A1 Jozwiak, Jacek J A1 Jukema, J Wouter A1 Gabor Kiss, Robert A1 Kownator, Serge A1 Iversen, Helle K A1 Maher, Vincent A1 Masana, Luis A1 Parkhomenko, Alexander A1 Peeters, André A1 Clifford, Piers A1 Raslova, Katarina A1 Siostrzonek, Peter A1 Romeo, Stefano A1 Tousoulis, Dimitrios A1 Vlachopoulos, Charalambos A1 Vrablik, Michal A1 Catapano, Alberico L A1 Poulter, Neil R A1 Ray, Kausik K A1 DA VINCI Study Investigators, K1 Atherosclerotic cardiovascular disease K1 Cardiovascular disease prevention K1 Cardiovascular risk K1 LDL-C K1 Lipid-lowering K1 Statins AB Low-density lipoprotein cholesterol (LDL-C) recommendations differ between the 2018 American College of Cardiology/American Heart Association (ACC/AHA) and 2019 European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines for patients with atherosclerotic cardiovascular disease (ASCVD) ( DA VINCI was a cross-sectional observational study of patients prescribed lipid-lowering therapy (LLT) across 18 European countries. Ten-year cardiovascular risk (CVR) was predicted among ASCVD patients receiving stabilized LLT. For patients with LDL-C ≥ 70 mg/dl, the absolute LDL-C reduction required to achieve an LDL-C of  Of the 2039 patients, 61% did not achieve LDL-C  In ASCVD patients, achieving ESC/EAS LDL-C goals could result in a 2% additional ARR over 10 years versus the ACC/AHA approach. YR 2022 FD 2022-05-14 LK http://hdl.handle.net/10668/20496 UL http://hdl.handle.net/10668/20496 LA en DS RISalud RD Jun 1, 2025