TY - JOUR AU - Serrano-Benítez, Almudena AU - Cortés-Ledesma, Felipe AU - Ruiz, Jose F. PY - 2020 DO - 10.3389/fmolb.2019.00153 UR - http://hdl.handle.net/10668/3746 T2 - Frontiers in Molecular Biosciences AB - Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5'-phosphate, 3'-hydroxyl moieties at the ends, which are, regardless of the pathway used, ultimately required for their repair. Cells are therefore endowed with a wide... LA - en PB - Frontiers KW - DNA double strand break (DSB) KW - Non-homologous DNA end joining KW - ATM KW - DNA-PK catalytic subunit KW - Genome instability KW - Roturas del ADN de doble cadena KW - Reparación del ADN por unión de extremidades KW - Proteínas de la ataxia telangiectasia mutada KW - Proteína quinasa activada por ADN KW - ADN KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Damage::DNA Breaks::DNA Breaks, Double-Stranded KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Repair::DNA End-Joining Repair KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::Ataxia Telangiectasia Mutated Proteins KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Serine-Threonine Kinases::DNA-Activated Protein Kinase KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::DNA TI - "An End to a Means": How DNA-End Structure Shapes the Double-Strand Break Repair Process TY - review article ER -